Where is CBD Useful?
Sources – Most of the descriptions below came from Dr. Bonni Goldstein’s “Cannabis Revealed” book copyrighted 2016 because of its excellent references to its sources of information. Before you medicate, educate. Buy the book to get details on the introductory paragraphs below. Know what you are putting in your body.
Anxiety and Depression – On page 135, “Cannabis has been used for anxiety and depression for thousands of years. A recent survey of patients seeking care in medical cannabis clinics in California reported that 38% (51% female, 33% male) of patients found relief from anxiety and 26% (35% female, 23% male) found relief from depression with cannabis use.”
Asthma – In “Cannabis Revealed” page 143, “In 1973, Dr. Donald Tashkin from UCLA authored a study in the New England Journal of Medicine that shows that cannabis works as a bronchodilator opening up the airways in both healthy and asthmatic people.”
Cancer Chemotherapy (Nausea and vomiting) – In the June, 2020 National Cancer Institute (NIH) website, for cancer-caused nausea and vomiting it said, “Delta-9-THC taken by mouth: Two cannabinoid drugs, dronabinol and nabilone, approved by the U.S. Food and Drug Administration (FDA), are given to treat nausea and vomiting caused by chemotherapy in patients who have not responded to standard antiemetic therapy. Clinical trials have shown that both dronabinol and nabilone work as well as or better than other drugs to relieve nausea and vomiting.
Cancer Pain – In the June 2020 National Cancer Institute (NIH) website, for cancer pain it said, “Delta-9-THC taken by mouth: Two small clinical trials of oral delta-9-THC showed that it relieved cancer pain. In the first study, patients had good pain relief, less nausea and vomiting, and better appetite. A second study showed that delta-9-THC could relieve pain as well as codeine. An observational study of nabilone also showed that it relieved cancer pain along with nausea, anxiety, and distress when compared with no treatment. Neither dronabinol nor nabilone is approved by the FDA for pain relief.”
Diabetes – It is a group of metabolic and autoimmune diseases that result in high blood sugar. On page 161, In Type 1, once triggered by say, a virus infection, the inflammatory system contributes to pancreatic cell destruction. The cannabis plant contains several anti-inflammatory compounds. In Type 2, it appears that cannabis users may be at lower risk of developing diabetes.
Epilepsy – Page 165 says, “There is compelling scientific evidence to suggest the dysfunction of the endocannabinoid system (ECS) plays a critical role in the development of seizures.” Read this whole section of the book as use of cannabinoids for neurological problems is complicated. Antiepileptic drugs (AEDs) are the mainstay of treatments. Cannabinoids have been use in conjunction with AEDs but only under the advise of a doctor. In animal studies, THC showed an effective anticonvulsant effect on 61% of the subjects, no effect on 29% and caused seizures in 10%. CBD has showed anticonvulsant activity in all animal research. Again, medical supervision is highly recommended.
Glaucoma – Page 185 says, “Multiple studies show that THC lowers intraocular pressure via the Type 1 cannabinoid receptor.”
Inflammatory and Autoimmune Conditions – Page 193 describes, “Cannabinoids as anti-inflammatory agents have been researched in numerous autoimmune diseases, including Type 1 diabetes, rheumatoid arthritis, allergic asthma, multiple sclerosis, colitis, chronic liver inflammation and cancers with inflammatory components.”
Migraine Headaches – Page 198 says, “A number of well-known trigger factors for migraine headaches, specifically sleep deprivation and anxiety or stress, are alleviated with cannabis, thereby reducing the number of migraine attacks…There is no question that THC-rich cannabis can help ab out or lessen the severity of a migraine, especially if taken at the onset of the pain.”
Multiple Sclerosis (MS) – Page 202 says, MS is the most common autoimmune inflammatory disease. There is a preparation of CBD and THC in a 1:1 ratio called Sativex used in 27 countries (not the US) for treatment of MS spasticity. It is also effective for intractable peripheral neuropathy and MS-induced pain.
Pain Relief – Dr. Goldstein reports on page 117 that, “In a review of patients seeking cannabis therapy in California in 2006, 82.6% of applicants reported using cannabis for pain relief. Many patients who are suffering with chronic pain report having less pain and a better quality of life with the use of medicinal cannabis.” On page 119, “Patients with pain from inflammation conditions can find relief from CBD-rich, THC-rich or a combination of the two. I encourage this group of patients to include some CBD in their treatment regimen as a potent anti-inflammatory”
Post-Traumatic Stress Disorder (PTSD) – Page 209 says, “The discovery of the ECS and the mapping of cannabinoid receptors has revealed that cannabinoid receptors are expressed in high levels in the part of the brain called the amygdala that controls anxiety, fear memory and emotional response to stress. When those receptors are triggered by natural endocannabinoids or by THC there is a reduction of anxiety and lessening of PTSD symptoms…a properly functioning ECS must be present.”
Schizophrenia – Page 215 says, “Hyperactivity of dopamine and serotonin, two important neurotransmitters, plays a critical role in the cause of schizophrenia. However, other neurotransmitters and their receptors are involved as well. Cannabinoid receptors exist in high numbers in the area of the brain impacted in schizophrenia, with accumulating evidence that ECS dysfunction is likely to play a role in this condition. Remember that if the ECS is not functioning properly, the brain cannot balance the hyperactivity of the involved neurotransmitters, which results in an imbalance in the messages that brain cells are sending to each other. There are also numerous studies that report that schizophrenia is likely an inflammatory illness. Recent research reveals that CBD is antipsychotic and that THC may be (but not always) pro-psychotic.”
Sleep Disorders – On page 224, “I have seen thousands of patients who report better sleep with cannabis use. Many of these patients suffer with pain, chronic illness and often anxiety, but I have also successfully treated patients with primary insomnia, sleep apnea, restless leg syndrome, nightmares and bruxism. They report they feel well rested upon awakening and for the most part do not experience morning grogginess.”
Skin Disorders – Page 222 says, “Both types of cannabinoid receptors have been found throughout the structure of human skin. The role of the ECS in skin is thought to regulate cell growth, wound healing and the differentiation of keratinocytes, the cells that make up the different skin layers. Since the ECS plays a large part in the immune response, cannabis medicine as treatment for inflammatory skin conditions has been the focus of recent research.” Application of creams is typically the method used.
Spinal Cord Injury – On page 226 Dr. Goldstein says, “Patients with spinal cord injury are finding relief with THC-rich cannabis and combination CBD+THC medicine based on personal preference and response. Most prefer to inhale due to the rapid onset with quick relief of spasticity and pain although a few of my patients have found relief with sublingual tinctures and/or edibles. I encourage patients with cervical or thoracic level injuries who want to inhale to use vaporizers as they are at increased risk for pulmonary infections. Terpenoids that are relaxing and sedating, such as linalool and myrcene, can be helpful for spasticity, anxiety and sleep.” Look at the video called “the-natural-option-with-nate-yeomans” in the video library above for a testimonial from a surfer on this subject.
Traumatic Brain Injury (TBI) – On page 235, it says, “In my clinical experience, patients with TBI benefit greatly with the use of cannabis. Patients report relief of pain, enhanced sleep, less agitation and mood stabilization. They report no adverse side effects from cannabis use… Depending on personal preference, some are using only CBD-rich cannabis and others are using combination CBD+THC cannabis. I encourage all of my patients with TBI to include CBD-rich cannabis in their regimen.
Tourette Syndrome (TS) – On page 230 the Doctor says, “The cause of TS is still unknown. Many patients who suffer with TS are finding relief of their symptoms with cannabis. A large percentage of people who have been diagnosed with TS also suffer with other significant conditions such as OCD, ADHD, mood disorders and anxiety. Adult patients in my practice are using mainly THC-rich cannabis products to help decrease the number of tics and other symptoms of TS and its related conditions, and they report no adverse side effects and an improved quality of life.”