CBD is a naturally occurring compound found in cannabis, a plant with a rich health-related history going back thousands of years. A safe, non-addictive substance, CBD is one of more than a hundred “phytocannabinoids,” which are unique to cannabis and endow the plant with its robust health-related profile.
CBD is closely related to another important active phytocannabinoid, tetrahydrocannabinol (THC), the compound that causes the “high” that cannabis is famous for. Both CBD and THC have significant health-related attributes. Unlike THC, CBD does not make a person feel “stoned” or intoxicated. That’s because CBD and THC act in different ways on different receptors in the brain and body.
Used together as they occur in the natural plant, they balance each other in a synergistic action called the “Entourage Effect” defined by Raphael Mechoulam, PhD, an Israeli researcher at the Hebrew University in Jerusalem in the early 1960s. A positive synergistic example is that CBD enhances pain relief when used with THC. An opposite example is that CBD can decrease the psychoactivity, memory loss and increased heart rate that THC can induce. (“Cannabis Revealed” by Bonni Goldstein, MD, page 15).
The Leafly diagram copyrighted and provided to the industry in 2014 by Leafly Holdings, Inc. is shown above to enhance the reader’s knowledge of effects of various CBDs and THCs relative to various maladies.